Association of air pollutions and systemic inflammation with early cardiovascular-kidney-metabolic syndrome among middle-aged and elderly adults: a cross-sectional study from CHARLS.

ABSTRACT: Ambient air pollution and systemic inflammation are recognized as risk factors for cardiovascular-kidney-metabolic (CKM) syndrome. However, the joint effect on middle-aged and elderly people in China remains unclear. This research aimed to explore the association between the long-term effects of air pollution/C-reactive protein (CRP) and early CKM syndrome. This cross-sectional cohort involved 9293 participants from the China Health and Retirement Longitudinal Study (CHARLS) in 2015 (Wave 3). The concentrations of air pollutants, including fine particulate matter (PM_2.5), inhalable particles (PM₁₀), sulfur dioxide (SO₂), nitrogen dioxide (NO₂), ozone (O₃) and carbonic oxide (CO), were obtained from the ChinaHighAirPollutants (CHAP), wh

SUBMITTER: Xu X 

PROVIDER: S-EPMC12603026 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature