Clinical characteristics and treatment challenges of esophageal sarcomatoid carcinoma: a single-center retrospective cohort study.

ABSTRACT:

Background

Esophageal sarcomatoid carcinoma (ESC) is an extremely rare malignant tumor of the esophagus, characterized by high malignancy, a propensity for metastasis, and poor prognosis. This retrospective study aims to analyze the clinicopathological features and prognostic factors of patients with ESC.

Methods

We retrospectively analyzed the clinicopathological characteristics of 57 patients with ESC who underwent surgical treatment at the Cancer Hospital, Chinese Academy of Medical Sciences between January 2000 and December 2021. Survival analysis was performed using Kaplan-Meier curves, and prognostic factors were evaluated using univariate and multivariate Cox regression analyses.

Results

The mean age of the cohort was 59.07±8.24 years, with males accounting for

SUBMITTER: Chen C 

PROVIDER: S-EPMC12603440 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature