Patients with multivalvular infective endocarditis demonstrate adverse cardiac remodeling before surgery with increased postoperative mortality risk.

ABSTRACT:

Background

Infective endocarditis can result in the destruction of any valve in the heart or damage to multiple valves. However, the scope of valvular damage is not considered in the current guidelines for surgical indications of infective endocarditis. Whether widespread valvular damage in infective endocarditis leads to more severe cardiac remodeling requiring earlier intervention remains unclear. We sought to investigate differences in adverse cardiac remodeling and postoperative outcomes in patients with infective endocarditis involving a single valve versus multiple valves.

Methods

From January 2010 to December 2022, 343 patients with infective endocarditis who underwent valve surgery in Beijing Anzhen Hospital were included in our study. The patients were divided into

SUBMITTER: Li Q 

PROVIDER: S-EPMC12603445 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature