Clinical efficacy of robot-assisted thymectomy for large thymomas: a dual analysis of national and single-institution data.

ABSTRACT:

Background

Robot-assisted thymectomy (RAT) has been widely accepted due to its safety and feasibility. However, the optimal approach for large thymomas remains unclear. This study compares peri-operative and long-term oncological outcomes of RAT and open thymectomy (OT) for large thymomas.

Methods

From the National Cancer Database (NCDB), 1,592 patients with thymomas >4 cm who underwent RAT (n=259, 16.3%) or OT (n=1,333, 83.7%) between 2010 and 2017 were identified. Tumor size was categorized as 4-5 cm, >5-6 cm, and >6 cm. A propensity-score-matched cohort analysis assessed tumor size, operative approach, and overall survival (OS) using Cox proportional hazards models and Kaplan-Meier survival curves. A single-institutional dataset of thymectomies for thymomas >5 cm (2008-20

SUBMITTER: Yang HC 

PROVIDER: S-EPMC12603466 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature