Impact of sarcopenia on early surgical outcomes in elderly patients following lung cancer surgery: a prospective cohort study.

ABSTRACT:

Background

Sarcopenia, characterized by reduced muscle mass, strength, and physical performance, has been linked to poor surgical outcomes. Its prevalence increases markedly with age and has been associated with various adverse health conditions in the elderly, including mental health issues like cognitive impairment, quality of life and depression. However, its impact based on international criteria remains unclear in elderly patients undergoing lung cancer surgery. Therefore, we aimed to prospectively evaluate the association between sarcopenia, defined by international guidelines, and postoperative outcomes, as well as geriatric mental health, in this population.

Methods

The LUng CAncer Surgery in sarcoPENia patients with old age (LUCAS-PEN) study (ClinicalTrials.gov iden

SUBMITTER: Woo HS 

PROVIDER: S-EPMC12603478 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature