Duration of extracorporeal membrane oxygenation support and survival outcomes: a retrospective analysis for lung transplant recipients with idiopathic pulmonary fibrosis.

ABSTRACT:

Background

Lung transplantation (LTx) is the only effective treatment for patients with end-stage idiopathic pulmonary fibrosis (IPF). However, little is known about the effect of extracorporeal membrane oxygenation (ECMO) on the prognosis of these patients. This study aimed to explore the association between ECMO duration and survival outcomes in IPF patients undergoing LTx.

Methods

This was a single-center retrospective cohort study that included 276 IPF patients who underwent LTx at the Affiliated Wuxi People's Hospital of Nanjing Medical University China, between January 2015 and December 2020. The primary outcome was overall survival (OS). Several Cox proportional hazards regression models with a cubic spline function were established to analyze the association between

SUBMITTER: Xiao X 

PROVIDER: S-EPMC12603493 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature