Incidence and prognosis of brain metastases in esophageal carcinoma: a systematic review and meta-analysis.

ABSTRACT:

Background

Brain metastases (BMs) are associated with rapid progression and substantial morbidity. In recent years, the incidence of brain metastases from esophageal carcinoma (BMECs) has increased, despite remaining relatively rare. However, there is still a limited understanding of the diagnostic and therapeutic strategies for BMECs. A comprehensive understanding of BMEC is critical to inform timely neuroimaging surveillance and guide treatment. This systematic review and meta-analysis aimed to characterize the incidence, presentation and prognosis of BMECs.

Methods

A Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA)-compliant systematic search was conducted across PubMed/MEDLINE, EMBASE, and Cochrane Library until January 2025. Studies reporting

SUBMITTER: Hong H 

PROVIDER: S-EPMC12603509 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature