Comparative study of perioperative and short-to-medium-term outcomes between thoracotomy and thoracoscopy after neoadjuvant therapy for stage IIB and IIIA non-small cell lung cancer.

ABSTRACT:

Background

The death rate of lung cancer ranks first among malignant tumors, and non-small cell lung cancer (NSCLC) accounts for more than 80% of all lung cancer cases. Approximately 30% of patients are diagnosed with locally advanced disease (stage III) at the time of initial evaluation, which restricts the feasibility of direct surgical intervention. Neoadjuvant therapy has the potential to downstage tumors and enhance prognosis; however, it may also elevate surgical risks. In recent years, video-assisted thoracoscopic surgery (VATS) has gained widespread acceptance due to its minimally invasive benefits. Nevertheless, the differences in efficacy between VATS and open thoracotomy following neoadjuvant therapy remain unclear. This study aims to explore the differences in periopera

SUBMITTER: Liu Y 

PROVIDER: S-EPMC12603537 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature