Effects of Maxillary Protraction Techniques on Maxillofacial, Dental, and Soft Tissue Outcomes in Patients With Non-Syndromic Unilateral Cleft Lip and Palate: A Systematic Review and Meta-Analysis.

ABSTRACT:

Objectives

To perform a quantitative assessment and best-evidence synthesis of maxillary protraction techniques for unilateral cleft lip, alveolus, and palate (UCLAP), incorporating all available studies regardless of methodological quality.

Materials and methods

Studies on growing non-syndromic UCLAP patients requiring maxillary protraction-against treated or untreated comparator groups-were identified across databases including PubMed, Embase, Scopus, Web of Science, EBSCOhost, Ovid MEDLINE, LILACS, Cochrane Library, and grey literature until April 23, 2025. Risk of bias for included studies was assessed using the Methodological Index for Non-randomised Studies and the Cochrane Risk of Bias tool. A random effects model was applied using RevMan for quantitative analysis.

SUBMITTER: Siddiqui HP 

PROVIDER: S-EPMC12603673 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature