Effects of Ageing, Oestrogen Level and Altered Dietary Loading on Rat Mandibular Cartilage-A Polarised Light Microscopy Study.

ABSTRACT:

Objective

The mandibular condylar cartilage (MCC) of rats was examined with polarised light microscopy (PLM) to study the effects of ageing, oestrogen level, and altered dietary loading on the structure of the MCC.

Materials and methods

96 Sprague-Dawley rats were separated into 12 groups based on their age (5 months [young] and 14 months [old]), oestrogen status (ovariectomised [OVX], non-ovariectomised [non-OVX]), and diet (hard, normal, or soft). The MCC specimens were examined using PLM to evaluate the orientation and retardation of collagen fibrils. The MCC was segmented sagittally into three distinct regions: anterior, most superior, and posterior. For each segment, the PLM values at varying depths were statistically compared across different groups using an N-way anal

SUBMITTER: Hauru R 

PROVIDER: S-EPMC12603676 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature