Trends in the use of opioid and non-opioid analgesics after TBI with and without polytrauma.

ABSTRACT:

Objective

To analyze whether outpatient opioid and non-opioid analgesic prescribing after traumatic brain injury (TBI) admission has varied over time among commercially insured patients in the USA.

Setting

2016-2022 Merative MarketScan commercial claims.

Participants

Commercially insured, opioid-naïve adults aged 18-64 hospitalized for TBI and/or long bone fracture (LBF).

Design

Retrospective observational study.

Main measures

We identified patients filling an opioid, benzodiazepine, muscle relaxant, gabapentinoid or non-steroidal anti-inflammatory drug within 30 days of discharge by injury type (TBI, LBF, both). We calculated the difference in prescription prevalence from 2016 to 2022 among patients with TBI compared with the difference among patients w

SUBMITTER: Medvecz AJ 

PROVIDER: S-EPMC12603714 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature