Association Between the Dietary Index for Gut Microbiota and Metabolic Syndrome: Mediation Effects of Albumin and Systemic Immune-Inflammation Index.

ABSTRACT: With the development of society, the prevalence of metabolic syndrome (MetS) has been increasing year by year and has become a major global health threat. The dietary index for gut microbiota (DI-GM), a recently proposed dietary assessment metric, has attracted considerable attention. However, its association with MetS has lacked systematic research evidence. This study was based on data from 59,842 nationally representative participants in the 2007-2018 National Health and Nutrition Examination Survey (NHANES) database, using methods such as multivariable weighted logistic regression, restricted cubic splines (RCS), subgroup analysis, and mediation effect analysis to explore the association between DI-GM and MetS. The study showed a significant negative correlation between the DI-GM score

SUBMITTER: Wei S 

PROVIDER: S-EPMC12603787 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature