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Histological prostatitis and its influence on benign prostatic hyperplasia: a systematic review and meta-analysis.


ABSTRACT:

Background

Inflammation is considered one of the potential etiological factors in the development and progression of benign prostatic hyperplasia (BPH). However, whether inflammation plays a critical role in the onset or progression of BPH remains controversial. Therefore, we conducted this systematic review and meta-analysis to comprehensively evaluate the impact of histological prostatitis on BPH.

Methods

We systematically searched cohort and cross-sectional studies published up to April 2025 in PubMed, the Cochrane Library, Embase, and Web of Science. The quality of the included cohort studies was assessed using the Newcastle-Ottawa Scale (NOS), and cross-sectional studies was evaluated with the Joanna Briggs Institute (JBI) checklist. Data were extracted on prostate volu

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12603820 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature