Sparing urethra in women at the time of cystectomy: retrospective comparison of cystectomies with and without urethrectomy.

ABSTRACT:

Background

In female patients undergoing cystectomy where orthotopic bladder reconstruction is not an option, urethrectomy is typically performed. Unlike in males, female urethrectomy carries a risk of damaging clitoral structures and nerves, potentially contributing to post-cystectomy sexual dysfunction. This study evaluates overall survival in women undergoing cystectomy with versus without urethrectomy.

Methods

A retrospective review of electronic medical records from 2000 to 2023 was conducted. Radical cystectomy specimens were reviewed for surgical details, tumor characteristics, urethral involvement, and urethrectomy status. Institutional criteria required urethrectomy in patients receiving neobladder reconstruction.

Results

Among 347 women who underwent cystect

SUBMITTER: Matoso A 

PROVIDER: S-EPMC12603828 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature