Excisional urethroplasty and the abdominoperineal approach to posterior urethral stenosis: surgical techniques and considerations for the radiated patient.

ABSTRACT: Pelvic radiation is associated with significant long-term genitourinary toxicity, with a cumulative incidence of urethral stricture following primary prostate radiation of nearly 20%. While there are a variety of techniques for posterior urethral reconstruction in the setting of prior pelvic radiation therapy, excisional urethroplasty remains a mainstay of treatment. Complete scar excision with primary anastomosis (EPA) for posterior stricture below the pelvic floor and a combined abdominoperineal approach for those extending above the pelvic floor are two reconstructive techniques for managing this complex pathology. Reconstructive success, defined as urethral patency on cystourethroscopy, for EPA is between 70-87%; however, the risk of de novo stress urinary incontinence (SUI) app

SUBMITTER: Findlay BL 

PROVIDER: S-EPMC12603845 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature