Endogenous endophthalmitis complicating infective endocarditis: a multicentre case-matched control cohort.

ABSTRACT:

Aims

Endogenous endophthalmitis (EE) is a rarely reported complication of infective endocarditis (IE). In an international series, we sought to determine the clinical and microbiological profile, treatment, and outcome of patients presenting with IE-related EE.

Methods and results

Cases recorded from 2014 to 2023 in nine centres in Europe and the United States were collected. Results were compared to a matched control group.

Conclusion

Sixty-six patients with EE were reported, mean age of 65.2 ± 14.9 years, 71% (n = 47) male. Blood cultures were positive in 97% (64 cases) of patients, with a predominance of streptococci (46%, n = 30).As compared with the control group (n = 264), the EE group presented with more frequent diabetes (35% vs. 21%, P

SUBMITTER: Layani I 

PROVIDER: S-EPMC12604093 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature