Risk factors for nosocomial meningitis in patients with external ventricular drainages.

ABSTRACT:

Background

External ventricular drain (EVD)-associated infections are a significant cause of morbidity and mortality. Nosocomial meningitis (NM) poses diagnostic challenges, and its prognosis heavily relies on the timely initiation of treatment. The aim of this study was to investigate the epidemiology of NM and risk factors in ICU patients.

Methods

We conducted a retrospective single-center cohort study of adult patients who received an EVD in a French ICU between 2018 and 2022. Patients were classified into those with NM or without meningitis based on biological and microbiological criteria. We assessed risk factors related to the patient, the device, and the primary pathology, treatment regimens, length of stay, and survival.

Results

Of 275 patients with EVD, 32 (1

SUBMITTER: Raffenot C 

PROVIDER: S-EPMC12604254 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature