Transcriptome of the ovaries and oviduct associates inflammatory response with high blood and meat spots incidence in chickens.

ABSTRACT: Blood and meat spots in egg white and yolk are regarded as defects affecting egg internal quality. The presence of blood and meat spots in egg directly reflects the health status of the hen's ovary and oviduct. In this study, we analyzed mRNA and lncRNA profiles from 36 samples (ovary, magnum/isthmus, and uterus) collected from 12 Rhode Island Red hens with higher and lower incidence of blood and meat spots (BMS) in eggs, to elucidate the factors associated with BMS incidence. There were 398, 359, 548 differentially expressed genes (DEGs) and 194, 34, 170 differentially expressed lncRNAs (DElncRNAs) across the ovary, magnum/isthmus and uterus identified between high and low BMS incidence groups. Through WGCNA analysis, we identified phenotype-associated gene modules in the ovary, the key t

SUBMITTER: Wu J 

PROVIDER: S-EPMC12604276 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature