Choroidal changes and association with Gaussian curvature in high myopic eyes with posterior staphyloma in ultra-wide-field optical coherence tomography angiography.

ABSTRACT:

Purpose

To evaluate choroidal changes in high myopic (HM) patients with posterior staphyloma (PS) and explore their association with Gaussian curvature (K) using ultra-wide-field optical coherence tomography angiography (UWF-OCTA).

Methods

HM patients with wide macular PS (Type I PS) and without any PS (control) were recruited. Highest K values (K_max) and choroidal parameters-vessel flow density (VFD), choroidal vascularity volume (CVV) and index (CVI), thickness, and volume-were compared in central and peripheral regions, and the fovea-centered 12-mm ETDRS quadrants of 24 × 20 mm UWF-OCTA images. Associations between choroidal parameters and K values in Type I PS eyes were analysed using multiple linear regression analysis, controlling for the confounding effect

SUBMITTER: Zhao Q 

PROVIDER: S-EPMC12604460 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature