Trends in global and national infertility and factors associated with primary infertile couples in recent middle-aged Chinese.

ABSTRACT:

Background

Infertility poses a significant burden on both global and national scales. However, the epidemiology of primary infertility among reproductive-aged couples in China remains poorly understood. Therefore, this study aimed to investigate the global infertility rate and identify factors associated with primary infertility among middle-aged couples in China.

Methods

Cross-sectional data were derived from the Global Burden of Disease (GBD) study and the Chinese Health and Retirement Longitudinal Study (CHARLS), two extensive databases that examined various disease burdens and associated factors at both global and national levels.

Results

From 1990 to 2019, the global infertility population has shown a steady annual increase. In China, the age-standardized prevale

SUBMITTER: Tang H 

PROVIDER: S-EPMC12604783 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature