Impact of bladder cuff management on oncologic outcomes following radical nephroureterectomy for upper tract urothelial carcinoma A systematic review and meta-analysis.

ABSTRACT:

Introduction

Bladder cuff excision (BCE) is an integral component of radical nephroureterectomy (RNU) for upper tract urothelial carcinoma (UTUC). While many approaches have been described, the optimal technique for BCE to provide maximal oncologic control remains unanswered. We performed a systematic review and meta-analysis to compare oncologic outcomes of different BCE techniques.

Methods

The Ovid MEDLINE, Embase, CENTRAL, and Web of Science databases were searched for studies comparing oncologic outcomes of RNU for UTUC based on different BCE approaches. Techniques for BCE were categorized as intravesical, extravesical, or endoscopic. Our primary outcomes were intravesical recurrence rate (IVR) and intravesical recurrence-free survival (IVRFS). Secondary outcomes include

SUBMITTER: Kim J 

PROVIDER: S-EPMC12604920 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature