Clinical outcome of 115 patients with synchronous bilateral Wilms' tumor: largest cohort of single-center experience.

ABSTRACT:

Introduction

Bilateral Wilms' tumor (BWT) represents 5 - 8% of patients with Wilms' tumor (WT). Despite the improvement of WT survival, still patients with BWT are challenging with a high risk of relapse and renal failure.

Purpose

To assess the outcome of pediatric patients with BWT treated at Children's Cancer Hospital Egypt (CCHE) 57357, and to assess the long-term nephrotoxicity among these patients.

Methods

This was a retrospective study including all patients with synchronous BWT treated at CCHE 57357 from 2007 until 2020. Records of all patients were reviewed. Patients were followed up until end of December 2024.

Results

In 115 eligible patients, median age was 31.5 months (range 3 month - 9 years). Male to female ratio was 1:1.67. Abdominal mass was the

SUBMITTER: Asfour HY 

PROVIDER: S-EPMC12604981 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature