Analysis of the microstates of prolonged disorders of consciousness.

ABSTRACT:

Objectives

Prolonged disorders of consciousness (pDOC) is a common disease in neurology. This study aimed to explore the microstate (MS) characteristics of pDOC patients based on resting-state Electroencephalography (EEG) and explore the changes in brain function in pDOC patients.

Methods

Patients were divided into healthy group and pDOC group according to the presence of consciousness. The T1 weighted 3D magnetization pre-gradient echo sequence (3d-t1-mprage) and resting state video EEG data were collected. First, the microstate clustering analysis was carried out. The global field power (GFP) was used to calculate microstate indicators (Duration, Occurrence, and Coverage), and then the statistical analysis between groups was carried out. Finally, the original resting state

SUBMITTER: Wu Y 

PROVIDER: S-EPMC12605022 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature