Association of maternal metal exposure and psychological status with adverse pregnancy outcomes: a nested case-control study.

ABSTRACT:

Background

Uncertainties persist regarding the relationship between serum metal concentrations, maternal mental health, and adverse pregnancy outcomes. This study investigated their impact on adverse birth outcomes to improve maternal-infant health.

Methods

A nested case-control study was conducted involving 468 pregnant women. Data on demographics and mental health, focusing on pregnancy-related anxiety and familial adaptation, partnerships, growth, affection, and resolve, were collected. We measured maternal serum concentrations of nine metals and trace elements. Mediator equations were used to explore the roles of maternal metal exposure and mental health in adverse pregnancy outcomes, including preterm birth, low birth weight, and large-for-gestational-age.

Results

SUBMITTER: Du Y 

PROVIDER: S-EPMC12605040 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature