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ABSTRACT: Background
With societal progress and a deepening understanding of Down syndrome (DS), research focus has shifted toward improving the quality of life and education for youth with DS. This study aims to determine the feasibility and estimate the preliminary effectiveness of a dyadic shared book reading program on the health-related quality of life of youth with DS (primary outcome), the mental wellbeing of university students (secondary outcome), and actor-partner outcomes to inform a future definitive trial.Methods
This study is an 8-week pilot dyadic randomized controlled trial (RCT) comparing a shared book reading intervention to a minimal activity control. The study will then continue for 12 months as a single-arm cohort study. Young people with DS and university studen
SUBMITTER: Huang X
PROVIDER: S-EPMC12605047 | biostudies-literature | 2025
REPOSITORIES: biostudies-literature