Hierarchical taxonomy of psychopathology and personalized mental health treatment selection.

ABSTRACT: Accumulated research has shown considerable heterogeneity in mental health treatment response. Precision mental health approaches aim to leverage this heterogeneity to tailor treatment selection to individual needs. The goals of this manuscript are to 1) present theoretical rationale for the potential usefulness of the Hierarchical Taxonomy of Psychopathology (HiTOP) to optimize treatment selection and 2) conduct a scoping review of the role of individual psychopathology components that map onto HiTOP on differential psychotherapy response, both as a proof-of-concept analysis, as well as to identify gaps and concrete recommendations for future application. We focus our review on treatment for internalizing disorders as a candidate class of disorders, and on Cognitive-Behavioral Therapies g

SUBMITTER: Argyriou E 

PROVIDER: S-EPMC12605141 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature