Excess volume addition method improves human resource efficiency and environmental sustainability of cytotoxic drug preparations.

ABSTRACT: IntroductionThe increasing incidence of cancer entails a rising burden of cytotoxic drugs preparation. To improve the preparation process of cytotoxic drugs, specially designed half-filled bags with overfill capacity were manufactured and used in clinical routine. The aim of this study was to investigate the impact of using such bags on the duration of preparation, human resources, costs and environmental sustainability.Methods and MaterialsA retrospective study comparing two methods, volume substitution and excess volume addition, for cytotoxic drug preparations was conducted over two periods of 6 months, within a University Hospital chemotherapy production unit. Volume substitution method (period 1; 5527 preparations) corresponded to the use of filled-bags. Excess volume addition method

SUBMITTER: Kroemer M 

PROVIDER: S-EPMC12605280 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature