A diagnostic test evaluation: dynamic optical functional imaging system for early-stage breast cancer detection.

ABSTRACT:

Background

The Dynamic Optical Breast Imaging (DOBI) ComfortScan system is a dynamic optical breast functional imaging system that analyses diffused light propagation through breast tissue. It continuously records the physiological properties of the tissue by applying a certain amount of pressure to the breasts that induces changes in blood hemoglobin concentration and the metabolic rates associated with the tumor angiogenesis of breast cancer. This study examined the clinical performance of dynamic optical functional imaging in the detection of malignant lesions, and compared the DOBI system with conventional imaging modalities. This novel diagnostic test addresses critical limitations of conventional imaging by providing functional assessment of tumor angiogenesis through hemoglo

SUBMITTER: He X 

PROVIDER: S-EPMC12605326 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature