Efficacy and safety of biologics in erythrodermic psoriasis: a systematic review and single-arm meta-analysis.

ABSTRACT:

Introduction

Erythrodermic psoriasis (EP) is a rare but severe inflammatory skin disease that affects the whole body. It presents clinically as widespread redness, scaling, and systemic symptoms. Treatment choices are currently limited, and conventional drugs often raise safety issues, highlighting the need for more effective and safer treatments. Biologics have emerged as a new approach. This study aimed to systematically evaluate the efficacy and safety of different biologics for EP by conducting a systematic review and single-arm meta-analysis.

Methods

We performed a systematic search of four databases-Embase, PubMed, Scopus, and the Cochrane Library-for relevant clinical studies published up to May 2025. Treatment effects were evaluated by analyzing statistical data such

SUBMITTER: Gao L 

PROVIDER: S-EPMC12605349 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature