Epidemiological and clinicopathologic characteristics, and prognostic factors of patients with extra-skeletal osteosarcoma: a Surveillance, Epidemiology, and End Results population study.

ABSTRACT:

Background

Extra-skeletal osteosarcoma (ESOS) has an extremely low incidence and unclear prognosis. We studied ESOS via Surveillance, Epidemiology, and End Results data to characterize it and build a prognostic nomogram.

Methods

The baseline information and survival outcome of patients were illustrated according to different primary tumor sites. The independent prognostic factors for ESOS were analyzed using univariate and multivariate Cox regression analyses. A nomogram was constructed using these prognostic factors to predict the survival of patients. The Kaplan-Meier method was performed to estimate survival, and both the log-rank test and the Wilcoxon-Breslow-Gehan test were used to compare the survival.

Results

A total of 4,567 patients with osteosarcoma who met

SUBMITTER: Liu Z 

PROVIDER: S-EPMC12605497 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature