Feasibility of next-generation sequencing using bronchoscopic specimens in potentially resectable non-small cell lung cancer.

ABSTRACT:

Background

With advances in multimodal treatment, the importance of identifying biomarkers by bronchoscopy has increased, even in potentially resectable non-small cell lung cancer (NSCLC). However, it remains unclear whether next-generation sequencing (NGS) using bronchoscopic specimens is as useful in potentially resectable NSCLC as in unresectable cases. The objective of this study was to evaluate the feasibility of performing NGS using bronchoscopic specimens obtained from patients with potentially resectable NSCLC.

Methods

The patients diagnosed with NSCLC via bronchoscopy at National Cancer Center Hospital who underwent NGS were retrospectively analyzed. We allocated all N0-2 and M0 and N3 and/or M1 cases to the potentially resectable and unresectable groups, respective

SUBMITTER: Yano K 

PROVIDER: S-EPMC12605578 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature