Lablab purpureus bioactive fractions as potent anticancer agents: an in vitro and in Silico study.

ABSTRACT:

Background

Plant-based bioactive compounds are essential for the discovery of drugs, especially in cancer research, because they include a wide range of chemicals and are very specific to certain types of cells. In earlier research, Lablab purpureus (LP), a legume rich in nutrients and with ethnomedicinal significance, showed encouraging antioxidant and anticancer potential. However, the specific bioactive components that cause these effects are still unknown. The objective of this study was to use a bioactivity-guided approach to isolate and characterise cytotoxic fractions from LP seed methanol extract, followed by in vitro and in silico evaluation.

Methods

Column chromatography and liquid-liquid partitioning were used to separate the fractions from the LP seed methanol ex

SUBMITTER: Bhat SS 

PROVIDER: S-EPMC12605697 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature