Functional network dynamics in photosensitive epilepsy depend on stimulation frequency and photoparoxysmal electroencephalographic response.

ABSTRACT:

Objective

Photosensitive epilepsy (PSE) is a reflex epilepsy, where abnormal electroencephalographic (EEG) responses are induced by photic stimulation. Photosensitivity is classified into four types based on the propagation of the brain's response to visual stimuli. Here, we aimed to describe the underlying dynamical mechanisms of PSE and different photosensitivity types.

Methods

This retrospective study included healthy controls (HC), PSE patients, and non-PSE patients with epilepsy (PWE). All participants were stimulated with flickering white light (1-60 Hz) under 10-20 EEG monitoring.

Results

We observed significantly higher occipital photoparoxysmal response (PPR) power in PSE patients compared to HC for stimulation frequencies between 10 and 20 Hz. However, the e

SUBMITTER: Timar L 

PROVIDER: S-EPMC12605740 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature