Rapid evaporative ionization mass spectrometry in surgery: a systematic review.

ABSTRACT:

Background

Rapid evaporative ionization mass spectrometry (REIMS) is an emerging technology facilitating real-time intraoperative tissue identification during surgery. This review aims to discuss the applications and reported outcomes of REIMS technology in a surgical context.

Methods

A systematic review was performed using four electronic databases that were searched in August 2025: MEDLINE, Emcare, Embase, and Web of Science. Eligible studies were peer-reviewed, included five or more patients, and evaluated REIMS technology in the context of a surgical specialty or pathology. Two independent reviewers screened studies, extracted data, and assessed risk of bias using the QUADAS-2 tool. The study protocol was registered in the PROSPERO international prospective register of s

SUBMITTER: Barber ARJ 

PROVIDER: S-EPMC12605806 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature