Autologous Fibrin Glue in Microvascular Decompression for Trigeminal Neuralgia and Hemifacial Spasm.

ABSTRACT: Adhesive materials are widely used in microvascular decompression for treating neurovascular compression syndromes. They play an important role in the critical step of vessel fixation. Recently, completely autologous fibrin glue produced solely from a patient's own plasma was developed. It can theoretically reduce the risks of viral or prion transmission and allergic reactions, while potentially providing more stable long-term adhesion. This study reports our initial experience with completely autologous fibrin glue in microvascular decompression and evaluates its efficacy and safety. Twenty-seven consecutive patients (12 with trigeminal neuralgia and 15 with hemifacial spasm) underwent microvascular decompression using autologous fibrin glue, including 8 trigeminal neuralgia treated using a

SUBMITTER: Matsushima K 

PROVIDER: S-EPMC12605820 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature