The Influence of Psychological Stress and Stress-Related Disorders in the Treatment Outcome of Periodontitis: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and objective

In humans 16 years and above with periodontitis (Population), how do psychological stress and stress-related disorders (PSRD; Exposure) compared to those without PSRD (Comparison) affect clinical attachment level (CAL) upon periodontitis treatment (Outcome), as observed in experimental studies or descriptive pre-post studies (Study design)?

Methods

Five major databases were searched for pre-post studies, descriptive cohort and quasi-experimental or randomised controlled trials (RCTs). For meta-analysis, mean differences in CAL and bleeding on probing (BOP) were pooled with random-effects models. Risk of bias, study quality and certainty of evidence were assessed.

Results

Thirteen studies (eight prospective, two retrospective, two quasi-experim

SUBMITTER: Mauland EK 

PROVIDER: S-EPMC12605825 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature