Using ECG-derived respiration for explaining BOLD-fMRI fluctuations during rest and respiratory modulations.

ABSTRACT: Recording physiological signals during fMRI is valuable for multiple purposes but often requires additional setup, increasing complexity and participant discomfort. This is particularly challenging in simultaneous EEG-fMRI studies, which typically already include electrocardiogram (ECG) recordings. Here, we aim to leverage the known modulation of ECG by respiration to obtain an ECG-derived respiration (EDR) signal without extra equipment. We acquired EEG-fMRI data from 15 healthy subjects during resting state and two respiratory challenges (slow-paced breathing and breath-holding), with simultaneous ECG and respiratory recordings. Multiple methods were used to extract EDR signals, and the results were evaluated by comparing them with recorded respiration and assessing the quality of physio

SUBMITTER: Esteves I 

PROVIDER: S-EPMC12606175 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature