Sentinel lymph node staging in urological cancer surgery: advances in imaging, intra-operative detection and translational research.

ABSTRACT:

Objectives

To review the clinical utility, outcome and possible future applications of sentinel lymph node biopsy (SLNB) in penile cancer (PeC), bladder cancer (BCa), prostate cancer (PCa), testicular cancer (TCa) and renal cell carcinoma (RCC), focusing in particular on current SLNB standards and exploring advancements in imaging agents, intra-operative detection, surgical navigation, and the potential application of SLNB in translational and clinical research.

Methods

A literature search was conducted in PubMed and EMBASE for studies published between 2000 and 2024, providing a narrative review of SLNB in oncological urology.

Results

In PeC, SLNB offers a lower adverse event rate compared to inguinal lymph node (LN) dissection, while maintaining high detection rates

SUBMITTER: van Gennep EJ 

PROVIDER: S-EPMC12606546 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature