Interventions for patients with prostate cancer on active surveillance: a narrative review.

ABSTRACT:

Objective

To examine contemporary evidence supporting non-surgical interventions for patients with early prostate cancer (PCa) on active surveillance (AS).

Methods

A literature search was conducted using the databases PubMed, Medline, and Embase in January 2024 to identify relevant articles published from 2011 onwards. Randomised controlled trials (RCTs) and cohort studies reporting on interventions in patients with PCa on AS were included.

Results

Several studies have investigated a range of non-surgical interventions, from exercise and food supplements to androgen receptor pathway inhibitors (ARPIs). The largest RCTs of ARPIs have shown the greatest effect in delaying disease progression to aggressive PCa, however, concerns exist around toxicity, long-term oncologic

SUBMITTER: Gill S 

PROVIDER: S-EPMC12606547 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature