The Genomic Imprint of Chromosomal Inversions and Demographic History in Island Populations of Deer Mice.

ABSTRACT: Populations that colonize islands experience novel selective pressures, fluctuations in size, and changes to their connectivity. Owing to their unique geographic setting, islands can function as natural laboratories in which to examine the interactions between demographic history and natural selection replicated across isolated populations. We used whole genome sequences of wild-caught deer mice (Peromyscus maniculatus) from two islands (Saturna and Pender) and one mainland location (Maple Ridge) in the Gulf Islands region of coastal British Columbia to investigate two primary determinants of genome-wide diversity: chromosomal inversions and non-equilibrium demographic history. We found that segregating inversions produce characteristic, large-scale distortions in allele frequencies and li

SUBMITTER: Howell EK 

PROVIDER: S-EPMC12606579 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature