Adding Early Postnatal Parameters of Ventilation to Prognostic Models for Pulmonary Outcome in Very Preterm Infants.

ABSTRACT:

Aim

To compare discrimination and calibration of prognostic models for pulmonary outcomes in very preterm (VPT) infants born < 32 weeks' gestation when including the mean airway pressure (MAP), the fraction of supplemental oxygen (FiO₂) and the respiratory severity score (RSS) reflecting parameters of ventilation and oxygenation during the first 24 and 72 h of life.

Methods

In this retrospective single center study of 168 VPT infants, the mean airway pressure (MAP), the fraction of supplemental oxygen (FiO₂) or RSS (considering MAP and FiO₂) were added to a baseline model of clinical risk factors to assess the improvements for prediction of bronchopulmonary dysplasia (BPD).

Results

The baseline model demonstrated good calibration (slop

SUBMITTER: Staude B 

PROVIDER: S-EPMC12606693 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature