Alcohol use and alcohol use disorders as a mediator between common mental disorders and antiretroviral therapy adherence among people living with HIV in Tanzania.

ABSTRACT:

Background

Common mental disorders (CMDs) and alcohol use disorder (AUD) are significant barriers to effective antiretroviral therapy (ART) adherence among people living with HIV (PLHIV), especially in sub-Saharan Africa. Suboptimal adherence to ART contributes to increased morbidity and mortality in this population. CMD and AUD frequently co-occur, with alcohol often serving as a maladaptive coping mechanism for psychological distress, thereby compounding the negative impact on treatment outcomes. Understanding the mediating role of AUD in the relationship between CMD and ART adherence is essential for designing targeted interventions aimed at improving HIV treatment success.

Methods

A hospital-based cross-sectional analytical study was conducted between August and October

SUBMITTER: Ghaimo FE 

PROVIDER: S-EPMC12606826 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature