A nomogram based on dual-layer spectral detector CT-derived 40KeV virtual monoenergetic images for preoperative prediction of simultaneous distant metastasis in colorectal cancer.

ABSTRACT:

Background

To establish and validate a nomogram combining dual-layer spectral detector CT(DLSCT)-derived 40KeV virtual monoenergetic images (VMI) of radiomics features, spectral parameters and clinical features for preoperative prediction of simultaneous distant metastases (SDM) in colorectal cancer (CRC).

Methods

We retrospectively included 137 patients [SDM⁺ (n = 51); SDM^-(n = 86)] with pathologically confirmed CRC who attended two hospitals between June 2022 and April 2023. Patients were divided into a training group (n = 90, from hospital A) and an external validation group (n = 47, from hospital B). Clinical characteristics and spectral parameters of arterial phase (AP), venous phase (VP) and delayed phase (DP) were collected to establish a clinica

SUBMITTER: Sun Q 

PROVIDER: S-EPMC12607172 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature