Prehabilitation for patients undergoing endoscopic submucosal dissection: a randomized controlled trial.

ABSTRACT:

Background

Endoscopic submucosal dissection (ESD) is a minimally invasive therapy for early gastrointestinal neoplasms, but patients may experience reduced functional capacity and delayed recovery post-procedure. Prehabilitation, has shown benefits in major surgery by improving physical fitness and recovery. We hypothesized that a structured prehabilitation regimen before ESD would enhance postoperative functional recovery and patient outcomes compared to standard care.

Methods

Single-center, assessor-blinded randomized controlled trial of 100 adults undergoing elective ESD, randomized to 4-week prehabilitation (supervised aerobic/resistance training 3×/week, individualized nutrition with protein supplementation, and psychological support) or usual care (standard instruction

SUBMITTER: Jiang B 

PROVIDER: S-EPMC12607201 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature