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Risk factors for avascular necrosis in pediatric femoral neck fractures: a systematic review and meta-analysis.


ABSTRACT:

Background

Avascular necrosis (AVN) is a severe complication following pediatric femoral neck fractures (PFNFs). Identifying risk factors for AVN is critical for guiding timely treatment and follow-up. However, prior studies report inconsistent associations. This systematic review and meta-analysis aimed to identify risk factors associated with AVN after PFNFs.

Methods

A comprehensive literature search was conducted in PubMed, Web of Science, EMBASE, and the Cochrane Library through April 30, 2025. Risk ratios (RRs) with 95% confidence intervals (CIs) were calculated to assess the association between potential risk factors and AVN. Leave-one-out sensitivity analyses, meta-regression, and subgroup analyses were performed.

Results

Thirty-four studies comprising 1332 ped

SUBMITTER: Dong B 

PROVIDER: S-EPMC12607231 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature