Development of Niosome-Entrapped Purple Waxy Corn Cobs (<i>Zea mays</i> L.) Extracts to Enhance UVB-Protection and Anti-Melanogenesis Activities.

ABSTRACT: Purple waxy corn cobs (PWCCs) represent an underutilized agricultural waste rich in anthocyanins with promising cosmeceutical potential. This study investigated niosome-based encapsulation to enhance the stability and bioactivity of PWCC anthocyanin extracts. PWCC extract was macerated in 50% ethanol. The extract exhibited a high total anthocyanin content (3.02 ± 0.81 mg C3GE/L), while cyanidin-3-glucoside identified as the major anthocyanin (1.17 ± 0.02 mg/g dry weight). Furthermore, the extracts showed strong antioxidant activities as evidence by DPPH, ABTS, and FRAP assays. The optimized niosome preparations synthesized by the probe sonication method exhibited better entrapment efficiency (80-85%), nanoscale particle size (185-296 nm), and stable zeta potential (-29 to -32 mV). TEM veri

SUBMITTER: Thongphachanh I 

PROVIDER: S-EPMC12607531 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature