Multi-Omics Profiling Identifies Apolipoprotein E as an Important Regulator of Steroidogenesis in Bactrian Camel Poll Glands During the Breeding Season.

ABSTRACT: Camel poll gland tissues (PGs) secrete amber liquid and volatile substances during the breeding season, inducing estrus and mating in female camels. These processes are mainly regulated by steroid hormones and their receptors, including the Androgen Receptor (AR). However, the functional components of PGs and their regulatory mechanisms in camel reproduction remain unclear. Therefore, in this study, we identified candidate differentially expressed metabolites (DEMs) and differentially expressed proteins (DEPs) associated with steroids through a multi-omics analysis of PGs during the male camel breeding season. We found that total cholesterol and testosterone concentrations were significantly increased in camel PGs at different stages of the breeding season. DEMs and DEPs related to cholest

SUBMITTER: Ma Q 

PROVIDER: S-EPMC12607609 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature