Genetic parameters and QTL mapping for novel metabolic traits in early-lactation Holsteins.

ABSTRACT: Early lactation in dairy cows is characterized by negative energy balance and compromised immune function that could lead to metabolic or inflammatory diseases. Circulating biochemical blood variables are increasingly used as indicators of metabolic and inflammatory diseases in many species. This study aimed to estimate genetic parameters and identify candidate genes and quantitative trait loci (QTL) associated with serum proteins (total protein, albumin, globulin, and albumin-to-globulin ratio), liver enzymes (gamma-glutamyltransferase [GGT], aspartate-amino-transferase [AST], glutamate dehydrogenase [GLDH]) and other serum variables (glucose, urea, nonesterified fatty acids [NEFA], β-hydroxybutyric acid [BHBA], and cholesterol). The study population consisted of genotyped lactating Holst

SUBMITTER: Liu R 

PROVIDER: S-EPMC12607924 | biostudies-literature | 2025 Jan

REPOSITORIES: biostudies-literature