The Role of the Oral Microbiome and Dental Caries in Respiratory Health: A Systematic Review.

ABSTRACT: Objectives: This systematic review aimed to evaluate the association between oral health-particularly dental caries and dysbiosis of the oral microbiome-and respiratory diseases across different age groups and clinical settings, with emphasis on microbial overlap, clinical outcomes, and preventive strategies. Methods: A systematic search was conducted in PubMed, Scopus, Embase, Web of Science, and the Cochrane Library up to June 2025. Eligible studies included randomized controlled trials, cohort, case-control, and cross-sectional investigations examining the relationship between oral diseases or microbiome alterations and respiratory outcomes. Data on study design, population, oral health parameters, microbial taxa, and respiratory endpoints were extracted. Study quality was

SUBMITTER: Zygmunt L 

PROVIDER: S-EPMC12608114 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature