Sex Differences in Prognostic Markers: Exploring Outcome Variability After Mechanical Thrombectomy in Large Vessel Occlusion Stroke.

ABSTRACT: Background: Sex-related disparities in long-term outcomes after large vessel occlusion (LVO) following mechanical thrombectomy (MT) have been repeatedly shown. Notably, a lower likelihood of achieving functional independence 90 days post-stroke has been found in women. However, most studies showed equal outcomes for both sexes after MT. It remains unclear whether there are sex differences in the prognostic values of clinical and neuroradiological parameters. Our investigation aimed to discern the divergent prognostic values of multiple markers between sexes. Methods: We retrospectively examined 183 stroke patients with LVO who received MT. Using multivariable logistic regression models, we investigated sex-specific associations of various parameters, including ASPECTS, lesion

SUBMITTER: Schacht H 

PROVIDER: S-EPMC12608539 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature